02. PTC Risks by Organ Type introduction

Page title (background color BLUE) : 

Introductory message text:talking about the risks by organ type in general (i.e.)

Did you know these facts about organ transplant recipients risk for skin cancers:

Skin cancer is the most common cancer affecting solid organ transplant recipients, affecting up to 70 percent of patients within 20 years, and is the result of intense immunosuppressive regimens.

  • Squamous cell carcinoma is 65 times more common in transplant recipients than in non-transplant patients
  • Kidney transplant patients are nearly four times more likely to develop melanoma
  • In Australia, after the fourth post-transplant year, 25% of heart transplant patients actually die from skin cancer
  • Only 54% of transplant recipients remembered receiving advice about skin cancer
  • Only 40% of kidney transplant recipients reported using sunscreen, and 90% of those used sunscreen with a sun protection factor of less than 10

Should we be concerned?:
From The Oncology Report: "Squamous cell carcinoma (SCC) is the most common cancer to occur after organ transplantation, Dr. Chesnut and his associates noted. The malignancy is 65-250 times more common, is more than 4 times more likely to metastasize, and has a mortality rate of 5% compared with a rate of less than 1% in immunocompetent patients . . ." (<- click to link to the full Jan 13, 2015 article)

Embedded link to 3 to 5 minute YouTube video (usually a medical professional related to the page topic)

One video  option from Loyola Health: "Transplant patients need to be aware of their greater risk for skin cancer"


Embedded link to full (30 min to one hour) presentation by medical professional on the page topic introduced above)

see for background on the Transplant Cancer Match study such as:

Solid organ transplantation provides life-saving therapy for patients with end-stage organ disease. Although transplant outcomes have improved dramatically over time, substantial morbidity results from chronic immunosuppressive therapy administered to prevent graft rejection. In large part due to this immunosuppression, transplant recipients have an elevated risk of cancer that is 2-4 times higher overall than the risk seen in the general population.

Much of this increased risk is related to a high risk for cancers caused by viral infections. The most common of these virus-related cancers is non-Hodgkin lymphoma, which is frequently caused by Epstein Barr virus. Other virus-related cancers include Kaposi sarcoma (caused by human herpesvirus 8); cancers of the cervix, vagina, vulva, penis, anus, and oral cavity (caused by human papillomavirus); and liver cancer (caused by hepatitis C and B viruses). Certain other malignancies, such as cancers of the lung, kidney, and thyroid, are also increased in transplant recipients. In addition, skin cancers (especially squamous cell and basal cell carcinomas, but also melanoma) occur at an elevated frequency.

Follow-up action plan and next step suggestions: suggest reading about risk for reader's own organ type, followed by highest risk cancer types for their organ

Resources related to this topic for further and deeper information/learning related to this topic

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DISCLAIMER: The content of this TRIO post-transplant cancer Web site is not influenced by sponsors. The site is designed primarily for use by transplant recipients and their supporters. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with your transplant team or a physician skilled in cancer and your organ type if you suspect you are ill.

Transplant Recipients International Organization, Inc.

7055 Heritage Hunt DR, #307
Gainesville VA 20155

800-TRIO-386  (800-874-6386)

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